Every line has a rule dictating which letters are allowed, and every clue can be answered with a word or name that has exactly one exception to the rule. Additionally, exactly one of the first letters of words in the clue is an exception to the rule:
| Clue | Allowed Letters | Rule | Clue Answer | Answer Exception | Clue Exception |
|---|---|---|---|---|---|
| Liza Of "Arrested Development" | CDGIJLMNOSUVWZ | has no degree > 2 vertices | MINNELLI | E | A |
| Name Of A Region Of R^2 Determined By A Quadratic Polynomial | ABDOPQR | not simply connected | PARABOLA | L | N |
| Laborer Fabricating Presents From Santa | FGJLPQR | has no reflectional or rotational symmetry | ELF | E | S |
| Wet Season In India | HINOSXZ | 180 rotational symmetry | MONSOON | M | W |
| One Escaping From The Police | CFGIJOPSTUVY | touches the baseline at only one point | FUGITIVE | E | E |
| Kind Of Domain (Examples Include Rings Of Integers) | BCDEHIKOX | vertical symmetry | DEDEKIND | N | R |
| Intermediate Job Upon Completion Of Graduate School, But Before Professorship | BCDGJOPQRSU | has a curve | POSTDOC | T | I |
| Hellenic Metropolis (Not Sparta) | ABEHIKMNOPTXY | looks identical to a capital Greek letter | ATHENS | S | S |
| "Margaritaville" Writer Buffett | HJKMNUVWXY | can collect rainwater | JIMMY | I | B |
| Delivery Business Whose Logo Has Hidden Pointer | BDEFHMNPRUWZ | contains parallel segments | FEDEX | X | L |
| Onetime President Ronald | ABEFGHPR | midline | REAGAN | N | O |
| Razor Brand Hosting Home Games For The New England Patriots | BDEFGHLPRT | contains a right angle | GILLETTE | I | N |
| Machines Taking Over Dumb Tasks | AHIMOTUVWXY | horizontal symmetry | AUTOMATION | N | D |
| Extremely Large Violin Or Viola | CDJLOUV | only boundary points of convex hull | CELLO | E | E |
The two answers are therefore THULIUM (element 69) and BLONDE.